| Campeonato Primera Division 2022 | ||||
| 1º Fecha | ||||
| 3-jun-2022 | Buenos Aires | Barracas Central | 1 | Tapia (P) |
| Central Cordoba | 1 | Lopez | ||
| 4-jun-2022 | San Miguel | Atletico Tucuman | 1 | Menendez |
| de Tucuman | Colon | 1 | Farias (P) | |
| 4-jun-2022 | Buenos Aires | San Lorenzo | 1 | Bareiro |
| Independiente | 1 | Benegas | ||
| 4-jun-2022 | Lomas de Zamora | Banfield | 1 | Galoppo (P) |
| Newell's Old Boys | 2 | Garcia, Sordo | ||
| 4-jun-2022 | Parana | Patronato | 1 | Herrera (P) |
| Velez Sarsfield | 1 | Janson | ||
| 4-jun-2022 | Vicente Lopez | Platense | 2 | Bergessio (P), Zarate (P) |
| Godoy Cruz | 1 | Abrego | ||
| 4-jun-2022 | Avellaneda | Racing Club | 2 | Chancalay, Gomez |
| Huracan | 0 | |||
| 5-jun-2022 | Santa Fe | Union | 1 | Alvez |
| Tigre | 2 | Colidio, Sosa | ||
| 5-jun-2022 | Cordoba | Talleres | 2 | Girotti, Diaz |
| Sarmiento | 0 | |||
| 5-jun-2022 | La Plata | Estudiantes | 1 | Rogel |
| Gimnasia y Esgrima | 1 | Tarragona | ||
| 5-jun-2022 | Buenos Aires | Boca Juniors | 2 | Sandez, Villa |
| Arsenal | 1 | Pitton | ||
| 5-jun-2022 | Florencio Varela | Defensa y Justicia | 0 | |
| River Plate | 0 | |||
| 6-jun-2022 | Rosario | Rosario Central | 0 | |
| Lanus | 0 | |||
| 6-jun-2022 | Buenos Aires | Argentinos Juniors | 2 | Carabajal, Nuss |
| Aldosivi | 1 | Cauteruccio (P) | ||
| 2º Fecha | ||||
| 9-jun-2022 | Rosario | Newell's Old Boys | 0 | |
| San Lorenzo | 0 | |||
| 10-jun-2022 | La Plata | Gimnasia y Esgrima | 2 | Carbonero, Tarragona (P) |
| de Tucuman | Patronato | 0 | ||
| 10-jun-2022 | Lanus | Lanus | 1 | Malcorra |
| Defensa y Justicia | 1 | Loaiza | ||
| 10-jun-2022 | Mar del Plata | Aldosivi | 0 | |
| Estudiantes | 1 | Lopez (A) | ||
| 10-jun-2022 | Buenos Aires | Huracan | 2 | Cristaldo, Blanco (A) |
| Rosario Central | 0 | |||
| 10-jun-2022 | Avellaneda | Independiente | 1 | Romero |
| Talleres | 0 | |||
| 11-jun-2022 | Avellaneda | Arsenal | 0 | |
| Banfield | 0 | |||
| 11-jun-2022 | San Fernando | Tigre | 1 | Retegui |
| Barracas Central | 1 | Sepulveda | ||
| 11-jun-2022 | Junin | Sarmiento | 1 | Lopez |
| Argentinos Juniors | 0 | |||
| 11-jun-2022 | Buenos Aires | River Plate | 0 | |
| Atletico Tucuman | 0 | |||
| 12-jun-2022 | Santa Fe | Colon | 2 | Farias (P), Abila |
| Union | 2 | Luna, Alvez (P) | ||
| 12-jun-2022 | Mendoza | Godoy Cruz | 2 | Rodriguez (2) |
| Racing Club | 0 | |||
| 12-jun-2022 | Buenos Aires | Velez Sarsfield | 0 | |
| Platense | 1 | Gomez | ||
| 12-jun-2022 | Santiago | Central Cordoba | 1 | Gonzalez |
| del Estero | Boca Juniors | 0 | ||
| 3º Fecha | ||||
| 18-jun-2022 | Avellaneda | Arsenal | 1 | Lomonaco (P) |
| Talleres | 1 | Goñi (A) | ||
| 18-jun-2022 | Junin | Sarmiento | 3 | Quinteros, Lozano (A), Toledo |
| Patronato | 1 | Garcia | ||
| 19-jun-2022 | San Fernando | Tigre | 0 | |
| Banfield | 1 | Datolo | ||
| 19-jun-2022 | Lanus | Lanus | 1 | Acosta |
| Colon | 0 | |||
| 19-jun-2022 | Buenos Aires | Huracan | 0 | |
| Atletico Tucuman | 0 | |||
| 19-jun-2022 | Santa Fe | Union | 1 | Peralta |
| River Plate | 5 | Romero, Fernandez, Alvarez (2), Palavecino | ||
| 19-jun-2022 | Buenos Aires | Barracas Central | 1 | Bandiera |
| Boca Juniors | 3 | Villa, Fernandez, Zeballos | ||
| 20-jun-2022 | Mendoza | Godoy Cruz | 2 | Ortiz, Rodriguez |
| Defensa y Justicia | 1 | Pizzini | ||
| 20-jun-2022 | Buenos Aires | Velez Sarsfield | 2 | Orellano, Fernandez |
| Rosario Central | 0 | |||
| 20-jun-2022 | La Plata | Gimnasia y Esgrima | 3 | Ramirez, Aleman (2, 1P) |
| Racing Club | 1 | Copetti | ||
| 20-jun-2022 | Avellaneda | Independiente | 2 | Benegas, Fernandez (P) |
| Estudiantes | 1 | Godoy | ||
| 20-jun-2022 | Rosario | Newell's Old Boys | 1 | Ditta |
| Argentinos Juniors | 0 | |||
| 21-jun-2022 | Mar del Plata | Aldosivi | 0 | |
| Platense | 0 | |||
| 21-jun-2022 | Santiago | Central Cordoba | 0 | |
| del Estero | San Lorenzo | 2 | Leguizamon, Bareiro (P) | |
| 4º Fecha | ||||
| 14-jun-2022 | Buenos Aires | San Lorenzo | 3 | Ortigoza (P), Elias, Leguizamon |
| Arsenal | 3 | Suarez, Colman (2) | ||
| 14-jun-2022 | Cordoba | Talleres | 0 | |
| Newell's Old Boys | 1 | Sordo | ||
| 14-jun-2022 | Parana | Patronato | 1 | Cobos |
| Aldosivi | 0 | |||
| 14-jun-2022 | La Plata | Estudiantes | 2 | Boselli (2, 1P) |
| Sarmiento | 1 | Torres | ||
| 14-jun-2022 | Mar del Plata | Defensa y Justicia | 1 | Rotondi |
| Huracan | 1 | Cristaldo | ||
| 15-jun-2022 | Buenos Aires | Barracas Central | 1 | Valenzuela (P) |
| Union | 2 | Alvez, Britez | ||
| 15-jun-2022 | Lomas de Zamora | Banfield | 2 | Cabrera, Galoppo (P) |
| Central Cordoba | 1 | Gonzalez | ||
| 15-jun-2022 | San Miguel | Atletico Tucuman | 2 | Carrera (2, 1P) |
| de Tucuman | Lanus | 1 | Varaldo | |
| 15-jun-2022 | Santa Fe | Colon | 1 | Abila |
| River Plate | 0 | |||
| 15-jun-2022 | Buenos Aires | Boca Juniors | 5 | Benedetto (2), Zeballos (2), Demartini (A) |
| Tigre | 3 | Figal (A), Retegui (2, 1P) | ||
| 16-jun-2022 | Buenos Aires | Argentinos Juniors | 2 | Nuss, Vera |
| Independiente | 1 | Benegas | ||
| 16-jun-2022 | Rosario | Rosario Central | 1 | Servio (P) |
| Godoy Cruz | 0 | |||
| 16-jun-2022 | Vicente Lopez | Platense | 1 | Esquivel |
| Gimnasia y Esgrima | 1 | Chavez | ||
| 16-jun-2022 | Avellaneda | Racing Club | 2 | Rojas, Dominguez |
| Velez Sarsfield | 0 | |||
| 5º Fecha | ||||
| 24-jun-2022 | Lomas de Zamora | Banfield | 1 | Enrique |
| Barracas Central | 1 | Abecasis (A) | ||
| 24-jun-2022 | Rosario | Rosario Central | 0 | |
| Gimnasia y Esgrima | 1 | Sosa | ||
| 24-jun-2022 | Buenos Aires | Boca Juniors | 1 | Salvio (P) |
| Union | 2 | Juarez (P), Troyansky (P) | ||
| 25-jun-2022 | Cordoba | Talleres | 0 | |
| Central Cordoba | 2 | Riaño (2) | ||
| 25-jun-2022 | Mar del Plata | Defensa y Justicia | 1 | Fernandez |
| Velez Sarsfield | 1 | Garayalde | ||
| 25-jun-2022 | La Plata | Estudiantes | 0 | |
| Newell's Old Boys | 2 | Sordo, Garro | ||
| 25-jun-2022 | Santa Fe | Colon | 0 | |
| Huracan | 1 | Garre | ||
| 25-jun-2022 | Buenos Aires | River Plate | 2 | Paradela, Romero |
| Lanus | 1 | Acosta | ||
| 26-jun-2022 | Buenos Aires | San Lorenzo | 1 | Bareiro (P) |
| Tigre | 1 | Blondel | ||
| 26-jun-2022 | Vicente Lopez | Platense | 0 | |
| Sarmiento | 0 | |||
| 26-jun-2022 | Avellaneda | Racing Club | 5 | Vecchio, Copetti, Sigali, Lucero (A), Gomez |
| Aldosivi | 0 | |||
| 26-jun-2022 | Buenos Aires | Argentinos Juniors | 1 | Reniero |
| Arsenal | 1 | Colman | ||
| 27-jun-2022 | Parana | Patronato | 3 | Rodriguez (2), Acevedo |
| Independiente | 1 | Romero | ||
| 27-jun-2022 | San Miguel | Atletico Tucuman | 1 | Carrera |
| de Tucuman | Godoy Cruz | 1 | Chavez | |
| 6º Fecha | ||||
| 1-jul-2022 | Santiago | Central Cordoba | 1 | Soraire |
| del Estero | Argentinos Juniors | 2 | Reniero, Torren (P) | |
| 1-jul-2022 | Buenos Aires | Boca Juniors | 0 | |
| Banfield | 3 | Galoppo, Enrique (2) | ||
| 2-jul-2022 | San Fernando | Tigre | 1 | Cabrera |
| Talleres | 1 | Catalan | ||
| 2-jul-2022 | Mendoza | Godoy Cruz | 1 | Allende |
| Colon | 0 | |||
| 2-jul-2022 | Buenos Aires | Velez Sarsfield | 0 | |
| Atletico Tucuman | 1 | Capasso | ||
| 2-jul-2022 | La Plata | Gimnasia y Esgrima | 1 | Muro |
| Defensa y Justicia | 0 | |||
| 3-jul-2022 | Santa Fe | Union | 3 | Juarez, Machuca, Agüero |
| Lanus | 0 | |||
| 3-jul-2022 | Buenos Aires | Barracas Central | 2 | Sepulveda, Bandiera |
| San Lorenzo | 1 | Bareiro | ||
| 3-jul-2022 | Junin | Sarmiento | 1 | Torres (P) |
| Racing Club | 1 | Copetti | ||
| 3-jul-2022 | Buenos Aires | Huracan | 3 | Galvan, Cristaldo (2, 1P) |
| River Plate | 2 | Gonzalez, Alvarez | ||
| 4-jul-2022 | Avellaneda | Arsenal | 2 | Colman, Picco |
| Estudiantes | 1 | Zapiola | ||
| 4-jul-2022 | Mar del Plata | Aldosivi | 2 | Rios, Maciel |
| Rosario Central | 1 | Baez | ||
| 4-jul-2022 | Rosario | Newell's Old Boys | 2 | Velazquez, Sordo |
| Patronato | 2 | Medina, Lozano | ||
| 4-jul-2022 | Avellaneda | Independiente | 1 | Rodriguez |
| Platense | 3 | Sabella, Tijanovich, Taborda | ||
| 7º Fecha | ||||
| 8-jul-2022 | Rosario | Rosario Central | 1 | Buonanotte |
| Sarmiento | 0 | |||
| 9-jul-2022 | Parana | Patronato | 0 | |
| Arsenal | 1 | Kruspzky | ||
| 9-jul-2022 | Buenos Aires | San Lorenzo | 2 | Giay, Bareiro |
| Boca Juniors | 1 | Rojo | ||
| 9-jul-2022 | Lomas de Zamora | Banfield | 2 | Enrique (2) |
| Union | 3 | Castrillon, Juarez, Cañete | ||
| 9-jul-2022 | Cordoba | Talleres | 0 | |
| Barracas Central | 2 | Mater, Sepulveda | ||
| 9-jul-2022 | Vicente Lopez | Platense | 1 | Esquivel |
| Newell's Old Boys | 1 | Ledesma (A) | ||
| 10-jul-2022 | La Plata | Estudiantes | 2 | Diaz, Castro |
| Central Cordoba | 2 | Torres, Martinez (P) | ||
| 10-jul-2022 | Avellaneda | Racing Club | 1 | Hauche |
| Independiente | 0 | |||
| 10-jul-2022 | San Miguel | Atletico Tucuman | 2 | Lotti, Ruiz Rodriguez |
| de Tucuman | Gimnasia y Esgrima | 0 | ||
| 10-jul-2022 | Lanus | Lanus | 2 | Aguirre, Sanabria |
| Huracan | 3 | Coccaro (2, 1P), Garre | ||
| 10-jul-2022 | Buenos Aires | River Plate | 0 | |
| Godoy Cruz | 2 | Ojeda, Abrego | ||
| 11-jul-2022 | Florencio Varela | Defensa y Justicia | 3 | Albertengo, Galvan, Tripichio |
| Aldosivi | 2 | Martinez, Kociubinski | ||
| 11-jul-2022 | Santa Fe | Colon | 2 | Garces, Abila |
| Velez Sarsfield | 1 | Gomez | ||
| 11-jul-2022 | Buenos Aires | Argentinos Juniors | 2 | Veron, Cabrera |
| Tigre | 1 | Retegui (P) | ||
| 8º Fecha | ||||
| 14-jul-2022 | Santiago | Central Cordoba | 1 | Veron |
| del Estero | Patronato | 3 | Medina, Herrera (2) | |
| 15-jul-2022 | Junin | Sarmiento | 2 | Quiroga, Toledo (P) |
| Defensa y Justicia | 0 | |||
| 15-jul-2022 | Mar del Plata | Aldosivi | 0 | |
| Atletico Tucuman | 1 | Ruiz Rodriguez | ||
| 15-jul-2022 | Avellaneda | Arsenal | 1 | Kruspzky |
| Platense | 1 | Costa | ||
| 16-jul-2022 | Buenos Aires | Barracas Central | 1 | Bandiera |
| Argentinos Juniors | 3 | Vera (2, 1P), Herrera | ||
| 16-jul-2022 | La Plata | Gimnasia y Esgrima | 0 | |
| Colon | 0 | |||
| 16-jul-2022 | Avellaneda | Independiente | 0 | |
| Rosario Central | 0 | |||
| 16-jul-2022 | Rosario | Newell's Old Boys | 0 | |
| Racing Club | 0 | |||
| 16-jul-2022 | Buenos Aires | Boca Juniors | 1 | Rojo (P) |
| Talleres | 0 | |||
| 17-jul-2022 | SanTa Fe | Union | 0 | |
| Huracan | 0 | |||
| 17-jul-2022 | Mendoza | Godoy Cruz | 2 | Rodriguez, Ojeda |
| Lanus | 1 | Sand (P) | ||
| 17-jul-2022 | Lomas de Zamora | Banfield | 1 | Gonzalez |
| San Lorenzo | 1 | Bareiro (P) | ||
| 17-jul-2022 | San Fernando | Tigre | 2 | Retegui, Colidio |
| Estudiantes | 1 | Piatti | ||
| 17-jul-2022 | Buenos Aires | Velez Sarsfield | 2 | Bou (P), Osorio |
| River Plate | 2 | Beltran, De la Cruz | ||
| 9º Fecha | ||||
| 19-jul-2022 | Santa Fe | Colon | 1 | Abila |
| Aldosivi | 1 | Maciel | ||
| 19-jul-2022 | Vicente Lopez | Platense | 2 | Taborda, Bogado |
| Central Cordoba | 0 | |||
| 19-jul-2022 | Avellaneda | Racing Club | 1 | Piovi |
| Arsenal | 1 | Kruspzky | ||
| 19-jul-2022 | San Miguel | Atletico Tucuman | 1 | Maestro Puch |
| de Tucuman | Sarmiento | 0 | ||
| 19-jul-2022 | Buenos Aires | Argentinos Juniors | 2 | Carabajal, Veron |
| Boca Juniors | 0 | |||
| 20-jul-2022 | Buenos Aires | San Lorenzo | 2 | Bareiro, Barrios |
| Union | 2 | Polenta, Gonzalez | ||
| 20-jul-2022 | Parana | Patronato | 1 | Alvarez |
| Tigre | 0 | |||
| 20-jul-2022 | La Plata | Estudiantes | 3 | Diaz, Rollheiser, Piatti |
| Barracas Central | 1 | Tapia | ||
| 20-jul-2022 | Florencio Varela | Defensa y Justicia | 2 | Duarte, Frias (P) |
| Independiente | 1 | Vigo | ||
| 20-jul-2022 | Lanus | Lanus | 2 | Acosta, Ortellado |
| Velez Sarsfield | 2 | Perrone, Jara | ||
| 20-jul-2022 | Buenos Aires | Huracan | 0 | |
| Godoy Cruz | 0 | |||
| 21-jul-2022 | Rosario | Rosario Central | 1 | Veliz |
| Newell's Old Boys | 0 | |||
| 21-jul-2022 | Cordoba | Talleres | 1 | Valoyes |
| Banfield | 0 | |||
| 21-jul-2022 | Buenos Aires | River Plate | 1 | Beltran |
| Gimnasia y Esgrima | 0 | |||
| 10º Fecha | ||||
| 23-jul-2022 | Junin | Sarmiento | 1 | Lopez |
| Colon | 3 | Rodriguez (P), Bernardi, Abila | ||
| 23-jul-2022 | Santiago | Central Cordoba | 1 | Lopez |
| del Estero | Racing Club | 3 | Copetti (2), Alcaraz | |
| 24-jul-2022 | Avellaneda | Independiente | 0 | |
| Atletico Tucuman | 1 | Lotti | ||
| 24-jul-2022 | San Fernando | Tigre | 3 | Cabrera, Menossi, Colidio |
| Platense | 0 | |||
| 24-jul-2022 | Mar del Plata | Aldosivi | 0 | |
| River Plate | 3 | Palavecino, Beltran, Borja | ||
| 24-jul-2022 | La Plata | Gimnasia y Esgrima | 1 | Aleman (P) |
| Lanus | 0 | |||
| 24-jul-2022 | Buenos Aires | Boca Juniors | 3 | Fernandez, Rojo, Villa |
| Estudiantes | 1 | Morel | ||
| 25-jul-2022 | Buenos Aires | San Lorenzo | 1 | Barrios |
| Talleres | 1 | Catalan | ||
| 25-jul-2022 | Rosario | Newell's Old Boys | 1 | Garro |
| Defensa y Justicia | 2 | Fernandez, Duarte | ||
| 25-jul-2022 | Lomas de Zamora | Banfield | 1 | Coronel |
| Argentinos Juniors | 1 | Torren (P) | ||
| 25-jul-2022 | Santa Fe | Union | 2 | Machuca, Zenon |
| Godoy Cruz | 1 | Larrosa | ||
| 25-jul-2022 | Buenos Aires | Velez Sarsfield | 1 | Bou (P) |
| Huracan | 1 | Garre | ||
| 26-jul-2022 | Avellaneda | Arsenal | 0 | |
| Rosario Central | 3 | Servio (2P), Veliz | ||
| 26-jul-2022 | Buenos Aires | Barracas Central | 2 | Colman, Rincon |
| Patronato | 1 | Acevedo | ||
| 11º Fecha | ||||
| 29-jul-2022 | Mendoza | Godoy Cruz | 1 | Barrios |
| Velez Sarsfield | 1 | Godin | ||
| 30-jul-2022 | Buenos Aires | Argentinos Juniors | 0 | |
| San Lorenzo | 1 | Vombergar | ||
| 30-jul-2022 | La Plata | Estudiantes | 0 | |
| Banfield | 0 | |||
| 30-jul-2022 | San Miguel | Atletico Tucuman | 2 | Carrera, Tesuri |
| de Tucuman | Newell's Old Boys | 0 | ||
| 30-jul-2022 | Buenos Aires | Huracan | 0 | |
| Gimnasia y Esgrima | 1 | Hezze (A) | ||
| 31-jul-2022 | Vicente Lopez | Platense | 0 | |
| Barracas Central | 0 | |||
| 31-jul-2022 | Lanus | Lanus | 0 | |
| Aldosivi | 1 | Silva | ||
| 31-jul-2022 | Avellaneda | Racing Club | 3 | Copetti, Miranda, Rojas |
| Tigre | 3 | Retegui (2, 1P), Protti | ||
| 31-jul-2022 | Parana | Patronato | 3 | Rodriguez, Sosa, Acevedo |
| Boca Juniors | 0 | |||
| 31-jul-2022 | Buenos Aires | River Plate | 1 | Mammana |
| Sarmiento | 2 | Mainero, Andueza | ||
| 1-ago-2022 | Rosario | Rosario Central | 0 | |
| Central Cordoba | 3 | Gonzalez, Soraire, Martinez (P) | ||
| 1-ago-2022 | Florencio Varela | Defensa y Justicia | 0 | |
| Arsenal | 0 | |||
| 1-ago-2022 | Santa Fe | Colon | 0 | |
| Independiente | 3 | Batallini, Fernandez, Benegas | ||
| 19-oct-2022 | Cordoba | Talleres | 2 | Valoyes, Santos |
| Union | 2 | Luna, Juarez | ||
| 12º Fecha | ||||
| 5-ago-2022 | La Plata | Gimnasia y Esgrima | 2 | Aleman (P), Contin |
| Godoy Cruz | 0 | |||
| 5-ago-2022 | Junin | Sarmiento | 2 | Lopez (2) |
| Lanus | 1 | Aguirre | ||
| 5-ago-2022 | Lomas de Zamora | Banfield | 0 | |
| Patronato | 0 | |||
| 6-ago-2022 | Avellaneda | Arsenal | 3 | Lomonaco, Goñi, Diaz |
| Atletico Tucuman | 1 | Orihuela | ||
| 6-ago-2022 | Buenos Aires | Barracas Central | 0 | |
| Racing Club | 0 | |||
| 6-ago-2022 | Santa Fe | Union | 2 | Castrillon, Marabel |
| Velez Sarsfield | 1 | Florentin | ||
| 6-ago-2022 | Cordoba | Talleres | 2 | Garro, Romero |
| Argentinos Juniors | 0 | |||
| 6-ago-2022 | Buenos Aires | Boca Juniors | 2 | Romero (2) |
| Platense | 1 | Morgantini | ||
| 7-ago-2022 | Mar del Plata | Aldosivi | 0 | |
| Huracan | 1 | Cristaldo (P) | ||
| 7-ago-2022 | Buenos Aires | San Lorenzo | 0 | |
| Estudiantes | 0 | |||
| 7-ago-2022 | Avellaneda | Independiente | 0 | |
| River Plate | 1 | Suarez | ||
| 7-ago-2022 | Rosario | Newell's Old Boys | 0 | |
| Colon | 0 | |||
| 8-ago-2022 | Santiago | Central Cordoba | 1 | Lopez |
| del Estero | Defensa y Justicia | 0 | ||
| 8-ago-2022 | San Fernando | Tigre | 3 | Castro, Retegui (2) |
| Rosario Central | 1 | Infantino | ||
| 13º Fecha | ||||
| 11-ago-2022 | Mendoza | Godoy Cruz | 2 | Rodriguez, Allende |
| Aldosivi | 0 | |||
| 11-ago-2022 | San Miguel | Atletico Tucuman | 1 | Tesuri |
| de Tucuman | Central Cordoba | 0 | ||
| 11-ago-2022 | Santa Fe | Colon | 1 | Sandoval |
| Arsenal | 1 | Gariglio | ||
| 12-ago-2022 | Vicente Lopez | Platense | 3 | Zarate (P), Benitez, Contreras |
| Banfield | 1 | Cuadra | ||
| 12-ago-2022 | Buenos Aires | Huracan | 4 | Cristaldo (2), Meza (A), Garre |
| Sarmiento | 1 | Torres (P) | ||
| 12-ago-2022 | Parana | Patronato | 3 | Kruspzky, Estigarribia, Giani |
| San Lorenzo | 2 | Vombergar, Castro (A) | ||
| 13-ago-2022 | Rosario | Rosario Central | 3 | Frias, Veliz, Infantino |
| Barracas Central | 1 | Colman | ||
| 13-ago-2022 | Florencio Varela | Defensa y Justicia | 0 | |
| Tigre | 0 | |||
| 13-ago-2022 | Lanus | Lanus | 1 | Sand |
| Independiente | 1 | Benegas | ||
| 13-ago-2022 | Buenos Aires | River Plate | 4 | Solari (2), Pinola, Suarez |
| Newell's Old Boys | 1 | Perez | ||
| 14-ago-2022 | Buenos Aires | Velez Sarsfield | 1 | Osorio |
| Gimnasia y Esgrima | 1 | Morales | ||
| 14-ago-2022 | Buenos Aires | Argentinos Juniors | 2 | Avalos (2) |
| Union | 0 | |||
| 14-ago-2022 | La Plata | Estudiantes | 1 | Heredia |
| Talleres | 0 | |||
| 14-ago-2022 | Avellaneda | Racing Club | 0 | |
| Boca Juniors | 0 | |||
| 14º Fecha | ||||
| 16-ago-2022 | Junin | Sarmiento | 1 | Gondou |
| Godoy Cruz | 2 | Rodriguez, Ojeda | ||
| 16-ago-2022 | Santiago | Central Cordoba | 3 | Riaño, Martinez (P), Lopez |
| del Estero | Colon | 0 | ||
| 16-ago-2022 | Buenos Aires | San Lorenzo | 2 | Hernandez, Cerutti (P) |
| Platense | 0 | |||
| 16-ago-2022 | Avellaneda | Independiente | 1 | Fernandez |
| Huracan | 1 | Hezze | ||
| 17-ago-2022 | Rosario | Newell's Old Boys | 2 | Ortellado (A), Balzi |
| Lanus | 0 | |||
| 17-ago-2022 | San Fernando | Tigre | 0 | |
| Atletico Tucuman | 0 | |||
| 17-ago-2022 | Avellaneda | Arsenal | 0 | |
| River Plate | 0 | |||
| 17-ago-2022 | Buenos Aires | Boca Juniors | 0 | |
| Rosario Central | 0 | |||
| 18-ago-2022 | Buenos Aires | Barracas Central | 3 | Colman, Tapia, Sepulveda |
| Defensa y Justicia | 1 | Gutierrez | ||
| 18-ago-2022 | Mar del Plata | Aldosivi | 3 | Cauteruccio (2), Cuesta |
| Velez Sarsfield | 2 | Brizuela, Osorio | ||
| 18-ago-2022 | Santa Fe | Union | 0 | |
| Gimnasia y Esgrima | 2 | Morales, Soldano | ||
| 18-ago-2022 | Cordoba | Talleres | 3 | Suarez, Santos, Diaz |
| Patronato | 3 | Medina, Castro, Estigarribia | ||
| 18-ago-2022 | Lomas de Zamora | Banfield | 0 | |
| Racing Club | 2 | Rojas, Chancalay | ||
| 18-ago-2022 | Buenos Aires | Argentinos Juniors | 1 | Nuss |
| Estudiantes | 0 | |||
| 15º Fecha | ||||
| 20-ago-2022 | Santa Fe | Colon | 2 | Rodriguez (2) |
| Tigre | 1 | Retegui | ||
| 20-ago-2022 | Buenos Aires | Huracan | 1 | Coccaro (P) |
| Newell's Old Boys | 0 | |||
| 21-ago-2022 | Lanus | Lanus | 1 | Perez |
| Arsenal | 0 | |||
| 21-ago-2022 | Mendoza | Godoy Cruz | 1 | Allende |
| Independiente | 1 | Insaurralde | ||
| 21-ago-2022 | Buenos Aires | River Plate | 3 | Solari, Borja, Zuculini |
| Central Cordoba | 0 | |||
| 21-ago-2022 | Mar del Plata | Defensa y Justicia | 0 | |
| Boca Juniors | 1 | Vazquez | ||
| 22-ago-2022 | La Plata | Estudiantes | 1 | Boselli (P) |
| Union | 0 | |||
| 22-ago-2022 | Rosario | Rosario Central | 0 | |
| Banfield | 1 | Urzi | ||
| 22-ago-2022 | Avellaneda | Racing Club | 1 | Copetti |
| San Lorenzo | 2 | Mendez, Vomberger | ||
| 22-ago-2022 | Vicente Lopez | Platense | 0 | |
| Talleres | 0 | |||
| 22-ago-2022 | Buenos Aires | Velez Sarsfield | 1 | Perrone |
| Sarmiento | 1 | Toledo (P) | ||
| 23-ago-2022 | Parana | Patronato | 0 | |
| Argentinos Juniors | 0 | |||
| 23-ago-2022 | San Miguel | Atletico Tucuman | 4 | Menendez, Ruiz, Pereyra, Coronel |
| de Tucuman | Barracas Central | 0 | ||
| 23-ago-2022 | La Plata | Gimnasia y Esgrima | 0 | |
| Aldosivi | 0 | |||
| 16º Fecha | ||||
| 26-ago-2022 | Santiago | Central Cordoba | 2 | Martinez, Lopez |
| del Estero | Lanus | 2 | Sand (P), Blando | |
| 26-ago-2022 | Avellaneda | Arsenal | 1 | Pitton |
| Huracan | 1 | Cristaldo | ||
| 27-ago-2022 | Buenos Aires | San Lorenzo | 1 | Gattoni |
| Rosario Central | 1 | Malcorra | ||
| 27-ago-2022 | Rosario | Newell's Old Boys | 1 | Perez |
| Godoy Cruz | 2 | Ojeda, Ramirez | ||
| 27-ago-2022 | Lomas de Zamora | Banfield | 1 | Domingo |
| Defensa y Justicia | 2 | Togni, Gutierrez (P) | ||
| 27-ago-2022 | Cordoba | Talleres | 1 | Valoyes (P) |
| Racing Club | 1 | Alcaraz | ||
| 27-ago-2022 | Buenos Aires | Argentinos Juniors | 0 | |
| Platense | 2 | Morgantini, Ayrton Costa | ||
| 27-ago-2022 | San Fernando | Tigre | 1 | Retegui (P) |
| River Plate | 1 | Solari | ||
| 28-ago-2022 | Junin | Sarmiento | 0 | |
| Gimnasia y Esgrima | 0 | |||
| 28-ago-2022 | Buenos Aires | Barracas Central | 1 | Goltz (A) |
| Colon | 0 | |||
| 28-ago-2022 | Avellaneda | Independiente | 1 | Soñora |
| Velez Sarsfield | 1 | Pratto | ||
| 28-ago-2022 | Buenos Aires | Boca Juniors | 2 | Langoni (2) |
| Atletico Tucuman | 1 | Lotti | ||
| 28-ago-2022 | Santa Fe | Union | 0 | |
| Aldosivi | 0 | |||
| 28-ago-2022 | La Plata | Estudiantes | 1 | Castro |
| Patronato | 0 | |||
| 17º Fecha | ||||
| 1-sep-2022 | Buenos Aires | Huracan | 2 | Cristaldo (2P) |
| Central Cordoba | 0 | |||
| 3-sep-2022 | Lanus | Lanus | 1 | Acosta |
| Tigre | 2 | Retegui, Castro | ||
| 3-sep-2022 | Rosario | Rosario Central | 1 | Marinelli |
| Talleres | 0 | |||
| 3-sep-2022 | Buenos Aires | Velez Sarsfield | 0 | |
| Newell's Old Boys | 1 | Garcia | ||
| 3-sep-2022 | Mar del Plata | Aldosivi | 1 | Cauteruccio |
| Sarmiento | 2 | Gondou (P), Lopez | ||
| 3-sep-2022 | Avellaneda | Racing Club | 1 | Lanzillota (A) |
| Argentinos Juniors | 0 | |||
| 3-sep-2022 | La Plata | Gimnasia y Esgrima | 3 | Dominguez, Morales, Contin |
| Independiente | 1 | |||
| 4-sep-2022 | Parana | Patronato | 0 | |
| Union | 0 | |||
| 4-sep-2022 | Vicente Lopez | Platense | 0 | |
| Estudiantes | 0 | |||
| 4-sep-2022 | Santa Fe | Colon | 1 | Rodriguez (P) |
| Boca Juniors | 2 | Briasco, Langoni | ||
| 4-sep-2022 | Buenos Aires | River Plate | 2 | De la Cruz, Borja |
| Barracas Central | 0 | |||
| 5-sep-2022 | Mar del Plata | Defensa y Justicia | 0 | |
| San Lorenzo | 0 | |||
| 5-sep-2022 | Mendoza | Godoy Cruz | 1 | Ojeda |
| Arsenal | 0 | |||
| 5-sep-2022 | San Miguel | Atletico Tucuman | 0 | |
| de Tucuman | Banfield | 0 | ||
| 18º Fecha | ||||
| 8-sep-2022 | Avellaneda | Independiente | 3 | Ferreyra, Fernandez, Batallini |
| Aldosivi | 0 | |||
| 8-sep-2022 | Santa Fe | Union | 1 | Nardoni |
| Sarmiento | 0 | |||
| 8-sep-2022 | Buenos Aires | Argentinos Juniors | 2 | Mac Allister, Veron |
| Rosario Central | 1 | Ortiz | ||
| 9-sep-2022 | Buenos Aires | Barracas Central | 2 | Mouche, Sepulveda |
| Lanus | 0 | |||
| 9-sep-2022 | Parana | Patronato | 1 | Quintana |
| Platense | 0 | |||
| 9-sep-2022 | San Fernando | Tigre | 1 | Retegui |
| Huracan | 1 | Cristaldo (P) | ||
| 9-sep-2022 | La Plata | Estudiantes | 1 | Boselli |
| Racing Club | 0 | |||
| 10-sep-2022 | Santiago | Central Cordoba | 3 | Martinez (2, 1P), Lopez |
| del Estero | Godoy Cruz | 0 | ||
| 10-sep-2022 | Buenos Aires | San Lorenzo | 1 | Bareiro |
| Atletico Tucuman | 1 | Carrera | ||
| 10-sep-2022 | Buenos Aires | Banfield | 2 | Quiroz, Cruz |
| Colon | 1 | Farias | ||
| 11-sep-2022 | Rosario | Newell's Old Boys | 2 | Piris (A), Reasco |
| Gimnasia y Esgrima | 0 | |||
| 11-sep-2022 | Avellaneda | Arsenal | 2 | Chimino, Diaz (P) |
| Velez Sarsfield | 2 | Gariglio (A), Brizuela | ||
| 11-sep-2022 | Buenos Aires | Boca Juniors | 1 | Benedetto |
| River Plate | 0 | |||
| 11-sep-2022 | Cordoba | Talleres | 1 | Valoyes (P) |
| Defensa y Justicia | 0 | |||
| 19º Fecha | ||||
| 12-sep-2022 | Junin | Sarmiento | 1 | Femia |
| Independiente | 2 | Fernandez (2) | ||
| 13-sep-2022 | Buenos Aires | Huracan | 1 | Merolla |
| Barracas Central | 1 | Mater | ||
| 13-sep-2022 | Mendoza | Godoy Cruz | 1 | Barrios |
| Tigre | 1 | Armoa | ||
| 13-sep-2022 | Vicente Lopez | Platense | 1 | Benitez |
| Union | 0 | |||
| 13-sep-2022 | Avellaneda | Racing Club | 1 | Hauche |
| Patronato | 0 | |||
| 14-sep-2022 | Mar del Plata | Aldosivi | 1 | Boolsen |
| Newell's Old Boys | 2 | Cauteruccio (A), Garcia | ||
| 14-sep-2022 | Santa Fe | Colon | 0 | |
| San Lorenzo | 0 | |||
| 14-sep-2022 | Buenos Aires | River Plate | 1 | Borja |
| Banfield | 2 | Cabrera, Palacios | ||
| 14-sep-2022 | Lanus | Lanus | 0 | |
| Boca Juniors | 1 | Benedetto | ||
| 15-sep-2022 | Rosario | Rosario Central | 1 | Frias |
| Estudiantes | 1 | Boselli | ||
| 15-sep-2022 | Mar del Plata | Defensa y Justicia | 2 | Rios, Togni |
| Argentinos Juniors | 1 | Avalos | ||
| 15-sep-2022 | San Miguel | Atletico Tucuman | 1 | Carrera (P) |
| de Tucuman | Talleres | 1 | Pizzini | |
| 15-sep-2022 | La Plata | Gimnasia y Esgrima | 2 | Sosa, Colazo |
| Arsenal | 0 | |||
| 25-oct-2022 | Buenos Aires | Velez Sarsfield | 3 | Janson, Bou (2, 1P) |
| Central Cordoba | 1 | Lopez | ||
| 20º Fecha | ||||
| 17-sep-2022 | Buenos Aires | Barracas Central | 3 | Sepulveda, Rodriguez (A), Glaby |
| Godoy Cruz | 1 | Ojeda (P) | ||
| 17-sep-2022 | Rosario | Newell's Old Boys | 0 | |
| Sarmiento | 1 | Arismendi | ||
| 18-sep-2022 | San Fernando | Tigre | 2 | Armoa, Colidio |
| Velez Sarsfield | 0 | |||
| 18-sep-2022 | Buenos Aires | San Lorenzo | 0 | |
| River Plate | 1 | Mammana | ||
| 18-sep-2022 | Buenos Aires | Banfield | 1 | Chavez |
| Lanus | 2 | Cabral, Orozco | ||
| 18-sep-2022 | Cordoba | Talleres | 2 | Garro (2) |
| Colon | 0 | |||
| 18-sep-2022 | Vicente Lopez | Platense | 0 | |
| Racing Club | 1 | Romero | ||
| 19-sep-2022 | Avellaneda | Arsenal | 3 | Machado, Lomonaco (P), Kruspzky |
| Aldosivi | 0 | |||
| 19-sep-2022 | Santa Fe | Union | 0 | |
| Independiente | 1 | Romero | ||
| 19-sep-2022 | Buenos Aires | Boca Juniors | 0 | |
| Huracan | 0 | |||
| 19-sep-2022 | Buenos Aires | Argentinos Juniors | 1 | Zalazar |
| Atletico Tucuman | 2 | Menendez (2) | ||
| 19-sep-2022 | La Plata | Estudiantes | 1 | Boselli |
| Defensa y Justicia | 2 | Frias, Rios | ||
| 20-sep-2022 | Parana | Patronato | 0 | |
| Rosario Central | 0 | |||
| 20-sep-2022 | Santiago | Central Cordoba | 1 | Torres |
| del Estero | Gimnasia y Esgrima | 0 | ||
| 21º Fecha | ||||
| 23-sep-2022 | Buenos Aires | Huracan | 3 | Perez, Cabral, Coccaro |
| Banfield | 1 | Cabrera | ||
| 23-sep-2022 | Mendoza | Godoy Cruz | 0 | |
| Boca Juniors | 1 | Langoni | ||
| 24-sep-2022 | Florencio Varela | Defensa y Justicia | 2 | Alanis, Otormin |
| Patronato | 1 | Herrera | ||
| 24-sep-2022 | Junin | Sarmiento | 2 | Lopez, Torres (P) |
| Arsenal | 0 | |||
| 24-sep-2022 | Lanus | Lanus | 2 | Di Placido, Blando |
| San Lorenzo | 0 | |||
| 24-sep-2022 | Buenos Aires | River Plate | 0 | |
| Talleres | 1 | Ortegoza | ||
| 24-sep-2022 | Avellaneda | Independiente | 1 | Benegas |
| Newell's Old Boys | 0 | |||
| 25-sep-2022 | Rosario | Rosario Central | 1 | Buonanotte |
| Platense | 1 | Gonzalez | ||
| 25-sep-2022 | La Plata | Gimnasia y Esgrima | 0 | |
| Tigre | 1 | Armoa | ||
| 25-sep-2022 | Avellaneda | Racing Club | 2 | Copetti, Carbonero |
| Union | 1 | Marabel | ||
| 25-sep-2022 | San Miguel | Atletico Tucuman | 3 | Coronel, Lotti (2, 1P) |
| de Tucuman | Estudiantes | 1 | Diaz | |
| 25-sep-2022 | Buenos Aires | Velez Sarsfield | 1 | Bou (P) |
| Barracas Central | 0 | |||
| 26-sep-2022 | Santa Fe | Colon | 0 | |
| Argentinos Juniors | 4 | Avalos, Veron, Cabrera, Roa | ||
| 26-sep-2022 | Mar del Plata | Aldosivi | 0 | |
| Central Cordoba | 3 | Lopez (3) | ||
| 22º Fecha | ||||
| 29-sep-2022 | Buenos Aires | Barracas Central | 1 | Bandiera |
| Gimnasia y Esgrima | 1 | Dominguez | ||
| 30-sep-2022 | San Fernando | Tigre | 3 | Armoa, Retegui (2) |
| Aldosivi | 0 | |||
| 30-sep-2022 | La Plata | Estudiantes | 2 | Zuqui, Noguera |
| Colon | 4 | Pierotti, Rodriguez (2), Abila | ||
| 30-sep-2022 | Santa Fe | Union | 0 | |
| Newell's Old Boys | 1 | Garcia | ||
| 30-sep-2022 | Avellaneda | Racing Club | 4 | Alcaraz, Vecchio, Romero, Moreno |
| Rosario Central | 3 | Almada, Buonanotte, Veliz | ||
| 1-oct-2022 | Santiago | Central Cordoba | 0 | |
| del Estero | Sarmiento | 0 | ||
| 1-oct-2022 | Vicente Lopez | Platense | 0 | |
| Defensa y Justicia | 0 | |||
| 1-oct-2022 | Buenos Aires | San Lorenzo | 1 | Cerutti |
| Huracan | 0 | |||
| 1-oct-2022 | Lomas de Zamora | Banfield | 1 | Chavez (P) |
| Godoy Cruz | 1 | Badaloni | ||
| 1-oct-2022 | Avellaneda | Arsenal | 0 | |
| Independiente | 1 | Vallejo | ||
| 2-oct-2022 | Parana | Patronato | 2 | Estigarribia, Medina |
| Atletico Tucuman | 1 | Coronel | ||
| 2-oct-2022 | Buenos Aires | Boca Juniors | 1 | Morales |
| Velez Sarsfield | 0 | |||
| 2-oct-2022 | Cordoba | Talleres | 0 | |
| Lanus | 1 | Troyansky (P) | ||
| 2-oct-2022 | Buenos Aires | Argentinos Juniors | 0 | |
| River Plate | 3 | Quintero, Beltran, Palavecino | ||
| 23º Fecha | ||||
| 3-oct-2022 | Rosario | Rosario Central | 1 | Almada |
| Union | 1 | Machuca | ||
| 4-oct-2022 | Mar del Plata | Aldosivi | 2 | Cauteruccio, Martinez |
| Barracas Central | 0 | |||
| 4-oct-2022 | Mendoza | Godoy Cruz | 0 | |
| San Lorenzo | 0 | |||
| 4-oct-2022 | Rosario | Newell's Old Boys | 0 | |
| Arsenal | 0 | |||
| 4-oct-2022 | Junin | Sarmiento | 2 | Toledo, Gondou |
| Tigre | 2 | Armoa, Colidio | ||
| 4-oct-2022 | Buenos Aires | Velez Sarsfield | 1 | Janson |
| Banfield | 0 | |||
| 5-oct-2022 | Santa Fe | Colon | 1 | Abila (P) |
| Patronato | 0 | |||
| 5-oct-2022 | Florencio Varela | Defensa y Justicia | 3 | Gutierrez, Alanis, Togni |
| Racing Club | 3 | Rojas, Vecchio, Moreno | ||
| 5-oct-2022 | San Miguel | Atletico Tucuman | 2 | Carrera, Coronel |
| de Tucuman | Platense | 1 | Taborda | |
| 5-oct-2022 | Buenos Aires | River Plate | 5 | Borja (2), Solari, Barco, Suarez |
| Estudiantes | 0 | |||
| 5-oct-2022 | Avellaneda | Independiente | 1 | Elizalde |
| Central Cordoba | 2 | Soraire, Insaurralde (A) | ||
| 6-oct-2022 | Lanus | Lanus | 0 | |
| Argentinos Juniors | 4 | Sanchez, Avalos (P), Moyano, Rodriguez | ||
| 6-oct-2022 | Buenos Aires | Huracan | 1 | Hezze |
| Talleres | 0 | |||
| 20-oct-2022 | La Plata | Gimnasia y Esgrima | 1 | Morales |
| Boca Juniors | 2 | Fabra, Langoni | ||
| 24º Fecha | ||||
| 8-oct-2022 | Buenos Aires | Barracas Central | 1 | Tapia (P) |
| Sarmiento | 1 | Toledo | ||
| 8-oct-2022 | Buenos Aires | San Lorenzo | 2 | Ortigoza (P) |
| Velez Sarsfield | 0 | |||
| 8-oct-2022 | Santa Fe | Union | 1 | Luna |
| Arsenal | 0 | |||
| 8-oct-2022 | Vicente Lopez | Platense | 1 | Benitez |
| Colon | 2 | Gonzalez (A), Abila | ||
| 9-oct-2022 | San Fernando | Tigre | 2 | Armoa (2) |
| Independiente | 1 | Soñora | ||
| 9-oct-2022 | Lomas de Zamora | Banfield | 0 | |
| Gimnasia y Esgrima | 2 | Ramirez, Aleman | ||
| 9-oct-2022 | Cordoba | Talleres | 3 | Valoyes, Godoy (P), Alvez |
| Godoy Cruz | 1 | Badaloni | ||
| 9-oct-2022 | Buenos Aires | Boca Juniors | 2 | Payero, Benedetto |
| Aldosivi | 1 | Valentini | ||
| 9-oct-2022 | Parana | Patronato | 0 | |
| River Plate | 1 | Borja | ||
| 10-oct-2022 | Buenos Aires | Argentinos Juniors | 1 | Veron |
| Huracan | 1 | Cordero | ||
| 10-oct-2022 | Rosario | Rosario Central | 0 | |
| Defensa y Justicia | 0 | |||
| 10-oct-2022 | La Plata | Estudiantes | 3 | Diaz (2), Boselli |
| Lanus | 1 | Sand | ||
| 10-oct-2022 | Avellaneda | Racing Club | 2 | Copetti, Mena |
| Atletico Tucuman | 0 | |||
| 10-oct-2022 | Santiago | Central Cordoba | 0 | |
| del Estero | Newell's Old Boys | 3 | Ramirez (A), Ditta, Esponda | |
| 25º Fecha | ||||
| 12-oct-2022 | Mar del Plata | Aldosivi | 0 | |
| Banfield | 1 | Tanco | ||
| 12-oct-2022 | La Plata | Gimnasia y Esgrima | 0 | |
| San Lorenzo | 1 | Bareiro | ||
| 12-oct-2022 | Junin | Sarmiento | 0 | |
| Boca Juniors | 1 | Langoni | ||
| 12-oct-2022 | Avellaneda | Independiente | 2 | Cazares, Marcone |
| Barracas Central | 2 | Vazquez, Colman | ||
| 12-oct-2022 | Buenos Aires | River Plate | 2 | De la Cruz, Suiarez |
| Platense | 1 | Zarate | ||
| 13-oct-2022 | Buenos Aires | Velez Sarsfield | 2 | Castro, Florentin |
| Talleres | 1 | Esquivel | ||
| 13-oct-2022 | Lanus | Lanus | 0 | |
| Patronato | 1 | Acevedo (P) | ||
| 13-oct-2022 | Mendoza | Godoy Cruz | 0 | |
| Argentinos Juniors | 0 | |||
| 13-oct-2022 | San Miguel | Atletico Tucuman | 1 | Maestro Puch |
| de Tucuman | Rosario Central | 1 | Buonanotte | |
| 13-oct-2022 | Rosario | Newell's Old Boys | 0 | |
| Tigre | 2 | Retegui (2, 1P) | ||
| 14-oct-2022 | Santa Fe | Colon | 0 | |
| Racing Club | 2 | Carbonero, Copetti | ||
| 14-oct-2022 | Mar del Plata | Defensa y Justicia | 1 | Alanis |
| Union | 0 | |||
| 14-oct-2022 | Buenos Aires | Huracan | 3 | Cristaldo (2P), Gudiño |
| Estudiantes | 1 | Diaz | ||
| 14-oct-2022 | Avellaneda | Arsenal | 2 | Kruspzky, Lomonaco |
| Central Cordoba | 0 | |||
| 26º Fecha | ||||
| 16-oct-2022 | Mar del Plata | Aldosivi | 1 | Cauteruccio (P) |
| Talleres | 3 | Espejo, Buffarini (P), Pizzini | ||
| 16-oct-2022 | Rosario | Newell's Old Boys | 2 | Garcia, Ditta |
| Boca Juniors | 0 | |||
| 16-oct-2022 | Mendoza | Godoy Cruz | 0 | |
| Patronato | 1 | Acevedo (P) | ||
| 16-oct-2022 | Avellaneda | Independiente | 1 | Batallini |
| Banfield | 0 | |||
| 16-oct-2022 | Buenos Aires | River Plate | 1 | Suarez |
| Rosario Central | 2 | Veliz (2) | ||
| 17-oct-2022 | Avellaneda | Arsenal | 1 | Caracho (A) |
| Barracas Central | 2 | Tapia (P), Diaz | ||
| 17-oct-2022 | La Plata | Gimnasia y Esgrima | 0 | |
| Argentinos Juniors | 0 | |||
| 17-oct-2022 | Buenos Aires | Velez Sarsfield | 4 | Janson (P), Osorio (2), Ortega |
| Estudiantes | 0 | |||
| 17-oct-2022 | San Miguel | Atletico Tucuman | 1 | Isa Luna |
| de Tucuman | Union | 1 | Corvalan | |
| 17-oct-2022 | Junin | Sarmiento | 2 | Gondou, Quinteros |
| San Lorenzo | 4 | Braida (2), Vombergar, Bareiro | ||
| 18-oct-2022 | Santa Fe | Colon | 1 | Rodriguez (P) |
| Defensa y Justicia | 2 | Alanis, Goltz (A) | ||
| 18-oct-2022 | Lanus | Lanus | 0 | |
| Racing Club | 1 | Copetti | ||
| 18-oct-2022 | Buenos Aires | Huracan | 2 | Cristaldo (P), Coccaro |
| Platense | 0 | |||
| 18-oct-2022 | Santiago | Central Cordoba | 1 | Gonzalez |
| del Estero | Tigre | 2 | Retegui (2, 1P) | |
| 27º Fecha | ||||
| 22-oct-2022 | Santa Fe | Union | 1 | Juarez |
| Central Cordoba | 4 | Gonzalez, Lopez (3) | ||
| 22-oct-2022 | Buenos Aires | San Lorenzo | 3 | Braida, Vombergar (2) |
| Aldosivi | 0 | |||
| 22-oct-2022 | La Plata | Estudiantes | 2 | Mas, Zapiola |
| Godoy Cruz | 0 | |||
| 22-oct-2022 | Mar del Plata | Defensa y Justicia | 3 | Fernandez (2), Dominguez |
| Atletico Tucuman | 1 | Coronel (P) | ||
| 22-oct-2022 | Buenos Aires | Argentinos Juniors | 2 | Mac Allister, Veron |
| Velez Sarsfield | 0 | |||
| 23-oct-2022 | Lomas de Zamora | Banfield | 0 | |
| Sarmiento | 0 | |||
| 23-oct-2022 | Cordoba | Talleres | 2 | Esquivel, Alvez |
| Gimnasia y Esgrima | 1 | Muro | ||
| 23-oct-2022 | Buenos Aires | Boca Juniors | 2 | Fernandez, Villa |
| Independiente | 2 | Fernandez (P), Vallejo | ||
| 23-oct-2022 | Parana | Patronato | 3 | Perez (A), Sosa, Batalla |
| Huracan | 2 | Cordero (2) | ||
| 23-oct-2022 | Avellaneda | Racing Club | 1 | Rojas (P) |
| River Plate | 2 | Borja (2) | ||
| 24-oct-2022 | Buenos Aires | Barracas Central | 1 | Valenzuela (P) |
| Newell's Old Boys | 1 | Sordo | ||
| 24-oct-2022 | Rosario | Rosario Central | 1 | Martinez |
| Colon | 1 | Pierotti | ||
| 24-oct-2022 | San Fernando | Tigre | 1 | Armoa |
| Arsenal | 4 | Navas, Pitton, Apaolaza, Kruspzky | ||
| 25-oct-2022 | Vicente Lopez | Platense | 1 | Suso |
| Lanus | 1 | Sand | ||